Water Based vs. Oil Based vs. Silicone Based Lubricants Jo Divine Silicone vs Water Based Lube Options for a Greater Experience Jill A quick run down on personal lubricants. . Remember, lubricants are usually used with sex, while vaginal moisturizers are used 2 3 times per week routinely. Some lubricants may also be used Using lube is a normal and healthy part of being sexually active, but the different options can be daunting. Here's a quick guide to the pros and cons of the most common K Y True Feel Silicone Based Lube K Y